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To develop and commercialize CD39-targeted therapeutics, including TTX-030, a first-in-class antibody for the treatment of cancer
January 3, 2019
By: Kristin Brooks
Managing Editor, Contract Pharma
AbbVie and Tizona Therapeutics, Inc. have entered into a global, strategic collaboration to develop and commercialize CD39-targeted therapeutics, including TTX-030, a first-in-class antibody for the treatment of cancer. The ATP-adenosine, a key immune regulatory switch in the tumor microenvironment (TME) controlls the inflammatory and suppressive activities of immune cells. CD39 is the enzyme responsible for the initial steps in the conversion of immune stimulatory extracellular ATP to imm...
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